For breeds with a high frequency of the JRD mutation:

My dog is a clear. Examine this dogs good and bad traits. Can he/she be bred to a carrier in your kennel that can complement their traits? Yes. At this time, many breeds with JRD have an very high frequency of the mutation, and in order to protect the gene pool, this type of breeding is necessary.

                       You keep the clear puppy from this cross that has the traits from both parents that you were hoping to get.

              My dog is a carrier.(#1 )  Ideally, this animal should be bred to a clear with traits that would complement this animal.
                                                       Clear progeny from this cross can be kept for future breeding.
                                            There is a 50% chance in this case of producing a clear in the first generation.
                              If  you dont have a clear, and no other options exist, this animal can be bred to another carrier.
                                           In this case, your chances of producing a clear for your next generation are 25%.
        There is a 25% chance that a animal that is homozygous for the mutant allele   (#2 )will be produced from this breeding.

My dog is homozygous for the mutant allele, #2, but otherwise is sound in body and temperament, and brings positive traits to the breed.   This is a two step breeding to get a clear.
This dog will need to be bred to a clear,  All of the puppies in the first generation will be carriers.  (#1's )
No need to DNA test at this point. A carrier #1  puppy from the first generation of this breeding can now be used in the second generation to produce clears  when bred to a clear


This is a very simple test, and it  will save lives!.  All breeders should be doing the  JRD tests, but unfortunately, only a handful really do.

JRD , Juvenile renal dysplasia (JRD) is an important category of kidney diseases in canines. Dysplasia is defined as abnormal growth or development of cells or organs. In the case of JRD the kidney fails to develop properly during embryogenesis in the womb.
At birth immature structures consisting of undifferentiated fetal cells or tissue types are found in the kidney, and are persistent throughout the life of the animal.

JRD can present itself with a wide range of symptoms and pathological findings. Definitive diagnosis of JRD is done by a wedge biopsy which reveals dysplastic lesions, including abnormal ducts, and glomeruli. Individuals with an abnormal biopsy can be asymptomatic, showing no signs of the disease. On the other hand, they may present with classic signs of chronic end stage renal failure, or somewhere between these two extremes. Given this broad spectrum of symptoms affected individuals often go unnoticed, and remain in the breeding population. This is why development of a genetic test was necessary for the management and elimination of this disease
When looking to adopt a puppy, you should ask to see, or  be furnished with , copies of the JRD  test results on the proud parents
                                        These results will have the parents registration name and number on them.
Since I have been actively researching JRD, I have heard of puppies suffer and die from this  juvenile disease
                                               from as early as 4 months  and up to 5 years old.
 
                    With all this valuable information I have laid out  for you, I can only hope and pray, if your looking  for a puppy,
to  please consider choosing a breeder that is actually breeding for the betterment of the breed, and not just saying it on their  website.
                                                                                     You can say anything you want on a website.
                                                                                  The burden of  proof is  in ink on the  test results
Click the link below to find out more on this  disease
We believe its better to know, than  NOT to know